| 摘要 |
Compounds of the formula I are disclosed, <CHEM> in which: P is a D or L isomer of Arg, Lys, HArg, MeArg, MeLys or MeHArg; A is a D or L isomer of Arg, Lys, HArg, MeArg, MeLys or MeHArg; B is OH, NH2 or NHAlk; Z is Phe, Phe(4 min -Alk), Tyr(Alk), Ile or Tyr; X is a D or L isomer of Phe, Phe(4 min -Alk), Val, Nva, Leu, Ile, Pba, Nle, Cha, Abu, Met, Chg, Tyr or Tyr(Alk); Y is Val, Ile, Abu, Ala, Chg, Gln, Lys, Cha, Nle, Thr, Phe, Leu or Gly; and R1 and R2 are, each, hydrogen, methyl or, when taken together, a cycloalkylene ring of 4-6 members taken with the beta -carbon to which they are attached. |
