发明名称 |
GANGLIOSIDE-RELATED COMPOUND AND PRODUCTION THEREOF |
摘要 |
NEW MATERIAL:A compound shown by formula I [R1 is H or group shown by formula II (Ac is acetyl; Alkali is alkali metal); R2 is H or group shown by formula III; Ac is acetyl]. USE:A maker for early detection of colon cancer, liver cancer, etc., and an agent for immunotherapy. PREPARATION:For example, a compound shown by formula IV [R1 is acetyl or group shown by formula V (R is OCOCH3); R2 is H group shown by formula VI (Ph is phenyl)] to give a compound shown by I. The compound shown by IV is obtained by reacting a monosaccharide shown by formula VII with a monosaccharide shown by formula VII (NPhth is phthalimido group), them with a disaccharide shown by formula IX and further carrying out various treatment.
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申请公布号 |
JPS63218692(A) |
申请公布日期 |
1988.09.12 |
申请号 |
JP19870053409 |
申请日期 |
1987.03.09 |
申请人 |
RIKAGAKU KENKYUSHO;MECT CORP |
发明人 |
OGAWA TOMOYA;SUGIMOTO MAMORU;NUMATA MASAAKI;NUNOMURA SHIGEKI;ITO MASAYOSHI;SHIDORI YOSHIYASU |
分类号 |
C07H13/06;A61K31/70;A61K31/7024;A61K31/7028;A61P43/00;C07H15/04;C07H15/10 |
主分类号 |
C07H13/06 |
代理机构 |
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代理人 |
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地址 |
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