| 摘要 |
Yeast proteins hydrophobically bonded to a desired protein or polypeptide produced in a transformed yeast are removed by treating the antigen with a chaotropic agent and concentrating the treated antigen in a hollow fiber capillary bundle having a molecular weight cutoff greater than 50,000 daltons but less than 1,000,000 daltons. The concentrated antigen is then diafiltered using a chaotropic agent to remove substantially all remaining yeast protein. |
