NEW SYNTHETIC BIOACTIVE COMPOUNDS AND METHOD OF PRODUCING BIOACTIVE EFFECT

摘要

A new class of broad spectrum bioactive polypeptides termed ''Magainin'' have been described. These peptides have a molecular weight of about 2500 or less, are highly water soluble, amphiphilic and non-hemolytic. A new method of producing antimicrobial effect by contacting a subject susceptible to microbial invasion or contamination with XPF, PGLa, a Magainin has also been.