| 摘要 |
<p>Recombinant mycobacterial vaccine vehicles capable of expressing foreign DNA which encodes at least one protein antigen for at least one pathogen against which an immune response is desired. The vaccine vehicles are useful for administration to mammalian hosts for purposes of immunization. A shuttle vector which replicates as a plasmid in a bacterium and which replicates as a phage in a mycobacterium is also disclosed. The shuttle vector is useful for transferring genetic material between different genera of microorganisms.</p> |
