| 摘要 |
Compounds of formula (I) in which Ar is optionally substituted phenyl, R1 is an optionally substituted aliphatic group and R2 and R3 are H or optionally substituted alkyl groups or R2 and R3 together with the nitrogen atom to which they are attached complete a heterocylic ring, are used in the treatment of Parkinson's disease. The compounds of formula (I) may be administered with a dopamine precursor such as levodopa and/or a dopa decarboxylase inhibitor such as carbidopa or benserazide. A preferred compound of formula (I) is N,N-dimethyl-1-[1-(4-chlorophenyl)-cyclobutyl]-3-methylbutylamine hydrochloride monohydrate. |
