发明名称 PHARMACOLOGICAL AGENT-LIPID SOLUTION PREPARATION
摘要 A pharmacological agent-lipid solution preparation comprising a lipophilic pharmacological agent, a desalted charged lipid and an aqueous-miscible lipid solvent such that upon introduction into an aqueous medium a suspension of lipid aggregates associated with the pharmacological agent are formed, the suspension exhibiting a stability of at least about 0.25 to 6 hours or longer without sedimentation. The preparations may contain an immunomodulator, an antifungal, anti-inflammatory, antineoplastic agent or hormone, and may be in unit (oral) dosage form including tablets, capsules, dragees or troches.
申请公布号 WO8806438(A1) 申请公布日期 1988.09.07
申请号 WO1988US00650 申请日期 1988.03.03
申请人 THE LIPOSOME COMPANY, INC. 发明人 POPESCU, MIRCEA, C.;TREMBLAY, PAUL, A.;JANOFF, ANDREW, S.;OSTRO, MARC, J.;CHAN, ELAINE;WEINER, ALAN, L.
分类号 A61K31/19;A61K9/107;A61K9/127;A61K9/42;A61K9/66;A61K31/405;A61K31/415;A61K31/565;A61K31/57;A61K31/60;A61K31/685;A61K31/70;A61K38/00;A61K47/10;A61K47/24;A61P5/00;A61P29/00;A61P31/04;A61P35/00;A61P37/00;B01J13/02;B32B9/02;(IPC1-7):A61K9/42;A61K37/22 主分类号 A61K31/19
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