发明名称 |
PHARMACOLOGICAL AGENT-LIPID SOLUTION PREPARATION |
摘要 |
A pharmacological agent-lipid solution preparation comprising a lipophilic pharmacological agent, a desalted charged lipid and an aqueous-miscible lipid solvent such that upon introduction into an aqueous medium a suspension of lipid aggregates associated with the pharmacological agent are formed, the suspension exhibiting a stability of at least about 0.25 to 6 hours or longer without sedimentation. The preparations may contain an immunomodulator, an antifungal, anti-inflammatory, antineoplastic agent or hormone, and may be in unit (oral) dosage form including tablets, capsules, dragees or troches. |
申请公布号 |
WO8806438(A1) |
申请公布日期 |
1988.09.07 |
申请号 |
WO1988US00650 |
申请日期 |
1988.03.03 |
申请人 |
THE LIPOSOME COMPANY, INC. |
发明人 |
POPESCU, MIRCEA, C.;TREMBLAY, PAUL, A.;JANOFF, ANDREW, S.;OSTRO, MARC, J.;CHAN, ELAINE;WEINER, ALAN, L. |
分类号 |
A61K31/19;A61K9/107;A61K9/127;A61K9/42;A61K9/66;A61K31/405;A61K31/415;A61K31/565;A61K31/57;A61K31/60;A61K31/685;A61K31/70;A61K38/00;A61K47/10;A61K47/24;A61P5/00;A61P29/00;A61P31/04;A61P35/00;A61P37/00;B01J13/02;B32B9/02;(IPC1-7):A61K9/42;A61K37/22 |
主分类号 |
A61K31/19 |
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