1,25-dihydroxyvitamin D2 compounds

摘要

The invention is directed to the preparation of hydroxylated compounds of the vitamin D2 series and specifically to a process for synthesizing 1 alpha ,25-dihydroxyvitamin D2, 1 beta ,25-dihydroxyvitamin D2, their corresponding 5,6-trans isomers and the C-24 epimers of these compounds. The hydroxylated vitamin D2 compounds obtained exhibit vitamin D-like activity and can be substituted for vitamin D3 or various of its known metabolites where such compounds are applied.