1-hydroxypyrazole-4-carboxylic acid

摘要

1-Hydroxypyrazole-4-carboxylic acid is prepared by heating an alkali metal of alkaline earth metal salt of 1-hydroxypyrazole, or a mixture of 1-hydroxypyrazole with an alkali metal or alkaline earth metal carbonate or bicarbonate, at from 120 DEG to 250 DEG C. for from 1 to 40 hours under a CO2 pressure of 20-300 bar, and is used for the preparation of pharmacologically useful compounds.