发明名称 |
Vaccine against varicella-zoster virus |
摘要 |
A gene of varicella-zoster virus (VZV) which encodes immunogenic outer surface viral proteins has been identified through DNA sequence analysis. Fragments of the DNA have been cloned into a vector which, when placed into a host organism, expresses proteins which react with human convalescent zoster sera and with monoclonal antibodies which neutralize viral infectivity. These proteins are useful for preparation of a vaccine for VZV.
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申请公布号 |
US4769239(A) |
申请公布日期 |
1988.09.06 |
申请号 |
US19840642983 |
申请日期 |
1984.08.21 |
申请人 |
MERCK & CO., INC. |
发明人 |
ELLIS, RONALD W.;KELLER, PAUL M. |
分类号 |
C12N15/09;A61K39/00;A61K39/25;C07H21/04;C07K1/22;C07K14/00;C07K14/03;C07K14/04;C07K16/00;C12N1/00;C12N1/20;C12N15/00;C12P21/02;C12R1/19;(IPC1-7):A61K39/12;C12P21/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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