发明名称 |
FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT ANVAENDBARA TIADIAZINON-, OXADIAZINON- OCH TRIAZINONDERIVAT. |
摘要 |
Heterocyclic compounds of the formula: <IMAGE> wherein A is a direct link, or is alkylene of 1 to 4 carbon atoms or alkenylene of 2 to 4 carbon atoms; wherein either X is -CR1R2- and Y is -O-, -S- or -NR3-, wherein R1, R2 and R3, which may be the same or different, each is hydrogen or alkyl of up to 4 carbon atoms; or X is -O-, -S- or -NH- and Y is -CR1R2- wherein R1 and R2 have the meanings stated above; and wherein Het is a 5- or 6-membered heterocyclic ring containing 1, 2 or 3 heteroatoms selected from nitrogen, oxygen or sulphur atoms, which ring may be unsubstituted or may bear one or two substituents as set out in claim 1, provided that when X is -CR1R2- and A is a direct link, Het is not unsubstituted 2-furyl; and salts thereof where appropriate; processes for their manufacture and pharmaceutical compositions containing them. The compounds possess cardiotonic and/or antihypertensive activity. |
申请公布号 |
FI76797(B) |
申请公布日期 |
1988.08.31 |
申请号 |
FI19820003897 |
申请日期 |
1982.11.12 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC |
发明人 |
HARGREAVES, RODNEY BRIAN;MCLOUGHLIN, BERNARD JOSEPH;MILLS, STUART DENNETT |
分类号 |
A61K31/53;A61K31/535;A61K31/54;A61P9/04;A61P9/12;A61P37/04;C07D213/40;C07D213/61;C07D213/81;C07D213/83;C07D215/48;C07D253/06;C07D273/04;C07D285/16;C07D307/68;C07D307/81;C07D333/24;C07D333/28;C07D333/38;C07D333/58;C07D333/68;C07D401/04;C07D405/04;C07D409/04;C07D409/06;C07D413/04;C07D413/06;C07D417/04 |
主分类号 |
A61K31/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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