发明名称 |
NYA -LAKTAMASINHIBITORFOERENINGAR. |
摘要 |
The present invention relates to hitherto unknown compounds of the general formula I: <IMAGE> I in which R1 stands for a phenyl, 4-hydroxyphenyl, 1,4-cyclohexadienyl or a 3-thienyl group; R2 represents a primary amino or a carboxy group; R3 is a hydrogen atom, or a lower alkyl, aryl or aralkyl radical, and A stands for a radical of a beta -lactamase inhibitor containing a beta -lactam ring as well as a carboxy group, A being connected via the carboxy group. The present invention provides new compounds useful in the treatment of bacterial infections. The new compounds are in particular strongly active against beta -lactamase producing bacteria. |
申请公布号 |
FI76807(B) |
申请公布日期 |
1988.08.31 |
申请号 |
FI19870000555 |
申请日期 |
1987.02.11 |
申请人 |
LEO PHARMACEUTICAL PRODUCTS LTD. A/S/(LOEVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) |
发明人 |
GODTFREDSEN, WAGN OLE;VON DAEHNE, WELF |
分类号 |
C07D;C07D498/04;C07D499/00;C07D499/21;C07D499/32;C07D499/64;C07D499/68;C07D499/72;C07D499/74;C07D503/00;C07D519/00;(IPC1-7):C07D499/00 |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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