发明名称 WATER SOLUBLE DERIVATIVES OF CEPHALEXIN AND PROCESS FOR THEIR PREPARATION
摘要 <p>The water soluble derivatives of cephalexin, having general formula: <IMAGE> wherein X represents an alkali metal or the organic nitrogen containing cation of a basic aminoacid, combine the typical antibiotic action of cephalexin with the water solubility and form essentially neutral, aqueous solutions. The process for the preparation of the above derivatives comprises a first step in which the methylol derivative of cephalexin is prepared and a second step in which the treatment with a suitable base is carried out.</p>
申请公布号 DE3176811(D1) 申请公布日期 1988.08.25
申请号 DE19813176811 申请日期 1981.10.06
申请人 MIBA SPA 发明人 REINER, ALBERTO
分类号 A61K;A61K9/08;A61K31/545;A61K31/546;A61P31/04;C07D;C07D501/00;C07D501/04;C07D501/22;(IPC1-7):C07D501/22 主分类号 A61K
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