PARTIAL CATIONIZATION OF PROTEIN-CONTAINING ANTIGENS AND METHOD OF IMMUNIZATION AND DESENSITIZATION

摘要

A method for preparing an antigenic protein-containing substance by partially cationizing a native protein-containing substance to an isoelectric point ranging from about 6.5 to about 9.5. The partially cationized substance exhibits increased antigenicity as compared to the native protein-containing substance and is useful in mammalian immunization and desensitization treatments by oral or parenteral administration.