| 摘要 |
PURPOSE:To obtain a 5alpha-reductase inhibitor useful for treating and preventing male-hormone related epidemics such as male alopecia, hirsutism, prostatic hypertropy, etc., containing an extract from leaves and/or pericarp of walnut as an active ingredient. CONSTITUTION:Leaves and/or pericarp of walnut is preferably dried, powdered, immersed and extracted with a solvent (e.g. polyethylene glycol) at normal temperature or under pressure or extracted with Soxhlet's extractor to give an extract. The extract may be directly used as it is as a 5alpha-reductase or mixed with ordinary drug additives and pharmaceutically manufactured into tablet, powder, granule, capsule, solution, etc., by a conventional procedure to give the aimed substance. A dose is 1mg-1g per adult one time and administered one time - several times/day in the case of prostatic hypertropy and a dose is 10mug-100mg and administered one time - several times/day in the case of apopecia treatment. |
