发明名称 |
Alkyl-substituted N-benzopyranyl lactams, processes for their preparation, their use and pharmaceutical preparations based on these compounds |
摘要 |
N-benzopyranyl lactams of the formula I <IMAGE> where R<1> is CN, NO2, SOn-Ar, (n = 1 or 2); R<2> is H, OH, alkoxy, alkyl, halogen or NR<5>R<6> (R<5> and R<6> are H, alkyl or alkylcarbonyl); R<3> and R<4> are alkyl; where the abovementioned meanings of R<1> and R<2> can also be exchanged; X is a chain (CH2)m which is substituted by alkyl and can be interrupted by O, NR<7> or S (R<7> is H or alkyl) are described in which the configuration on C3 and C4 is always opposite. Preparation processes are likewise given. Compounds I are used for the treatment of high blood pressure.
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申请公布号 |
DE3703229(A1) |
申请公布日期 |
1988.08.18 |
申请号 |
DE19873703229 |
申请日期 |
1987.02.04 |
申请人 |
HOECHST AG |
发明人 |
CHRISTIAN,DR. ENGLERT,HEINRICH;LANG,HANS-JOCHEN,DR.;MANIA,DIETER,DR.;SCHOELKENS,BERNHARD,DR. |
分类号 |
A61K31/40;A61K31/4025;A61K31/42;A61K31/425;A61K31/535;A61K31/54;A61P9/12;A61P13/02;A61P15/00;C07D405/04;C07D413/04;C07D417/04;(IPC1-7):C07D405/04;C07D521/00;A61K31/395;A61K31/35 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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