| 摘要 |
NEW MATERIAL:The compound of formula I {R<1> is alkoxy; R<2> is (halogeno)- alkyl, alkylamino or cycloalkyl; X is F or Cl; Y is group of formula II (R<2> is H, alkyl, aralkyl, etc.; R<3> is H or alkyl; A is ethylene, trimethylene or COCH2; m is 1 or 2), formula III [W is group of formula IV (R<5> and R<6> are H, alkyl, etc.; n' is 0 or 1), OH or alkoxy; R<4> is H, alkyl, OH, etc.; B is methylene, ethyl ene or trimethylene; n is 1 or 2]} and its salt or ester. EXAMPLE:1-Cyclopropyl-6-fluoro-8-methoxy-7-(1-piperazinyl)-1,4-dihydro -4-oxoqui noline-3-carboxylic acid hydrochloride. USE:A remedy for microbism. PREPARATION:The compound of formula I can be produced e.g. by reacting a compound of formula V (X' is F) with an amine compound of formula YH.
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