| 摘要 |
PURPOSE:To easily produce the titled substance useful as an intermediate for pharmaceuticals, agricultural chemicals, perfumes, etc., in a short time in high yield, by reducing an acylfuran derivative with sodium borohydride in methanol in the presence of a basic substance. CONSTITUTION:The objective compound of formula II can be produced by reducing a compound of formula I (n is 4-8) with 1-1.5 times equivalent of sodium borohydride (based on the compound of formula I) in methanol in the presence of 0.05-5wt.% basic substance (e.g. alkali metal methylate, tertiary organic amine, etc.) (based on the compound of formula I) at -10-+50 deg.C. The objective compound can be produced by using reduced amount of sodium borohydride.
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