发明名称 |
FUSION PARTNER AND ITS PRODUCT |
摘要 |
<p>By careful screening and mutation, a humanmurine hybridoma suitable as a fusion partner for immortalizing an antibody-secreting as a cell has been generated. The trioma fusion products of this immortalizing partner are stable producers of human monoclonal antibodies. A trioma which produces monoclonal human anti-varicella zoter is disclosed. A human anti-A IgM is also produced using this general method by the trioma S-H22 and by an alternate hybrid, HHA1.</p> |
申请公布号 |
CA1240628(A) |
申请公布日期 |
1988.08.16 |
申请号 |
CA19850471399 |
申请日期 |
1985.01.03 |
申请人 |
BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (THE);CETUS CORPORATION |
发明人 |
ENGLEMAN, EDGAR G.;FOUNG, STEVEN K.H.;GRUMET, F. CARL;RAUBITSCHEK, ANDREW R.;LARRICK, JAMES W. |
分类号 |
C07K16/08;C07K16/34;(IPC1-7):C12P21/02;A61K39/395;C12N5/02 |
主分类号 |
C07K16/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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