发明名称 3-AMINO-2,3-DIHYDRO-I-BENZOXEPIEN AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS
摘要 3-amino-2,3-dihydro-1-benzoxepine compounds corresponding to the general Formula I <IMAGE> I wherein R1 and R2 may each be hydrogen, halogen, lower alkyl or lower alkoxy, or if one of R1 and R2 is hydrogen, the other may also be nitro or trifluoromethyl, R3 represents hydrogen or a lower alkyl group which optionally may be substituted by hydroxy, lower alnoxy, an optionally substituted phenyl group or an optionally substituted amino group, and R4 represents hydrogen or lower alkyl, or R3 and R4 together with the nitrogen atom form a 5 or 6 member heterocycle. The compounds exhibit pharmacological, especially antidepressive, activity.
申请公布号 PH22384(A) 申请公布日期 1988.08.12
申请号 PH19850000329 申请日期 1985.10.28
申请人 KALI-CHEMIE PHARMA GMBH 发明人 OHLENDORF HEINRICH WILHELM;RUHLAND MICHAEL;WOLF KLAUS-ULRICH
分类号 A61K31/335;A61K31/395;A61K31/445;A61K31/495;A61K31/535;A61K31/54;A61P25/24;A61P25/26;C07D313/08 主分类号 A61K31/335
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