摘要 |
<p>Octapeptides of the formula: R-A<1>-Cys-Tyr-D-Trp-Lys-alpha-Aminobutryric Acid-Cys-A<2>, wherein R is H or a C1-20 alkyl; A<1> is D-beta-Nal, D-Trp, or D-X-Phe, where X is H, OH, CH3, or a halogen; and A<2> is Thr-NH2, Thr-OH, Nal-NH2, or Trp-NH2 are effective therapeutically in reducing growth hormone,insulin, glucagon and/or pancreatic exocrine secretion.</p> |