| 摘要 |
NEW MATERIAL:An optically active alcohol compound shown by I (R is H or 1-18C straight-chain alkyl; * is asymmetric carbon). EXAMPLE:6-Chloro-4-methyloctanol. USE:Useful for various industrial chemicals such as an intermediate for cosmetics and drugs. Further useful as an intermediate for liquid crystal compound or as an optical resolving agent or an auxiliary for asymmetric synthesis. Being expected to have physiological activities. PREPARATION:For example, (R)-(+)-citronellic acid or an R-2,6-dimethyl-8-oxo- alkene obtained by alkylating (R)-(+)-citronellic acid is reduced or optically active 3,7-dimethyl-6-octenal is reduced to give a compound, which is chlorinated to give a 2,6-dimethyl-8-chloroalkene-2. This compound is oxidized and reduced to give a compound shown by formula I.
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