| 摘要 |
<p>NEW MATERIAL:A compound expressed by formula I (A is lower alkylene; R<1> and R<2> are lower alkyls). EXAMPLE:gamma-L-glutamyl-o-methyl-p-(N-ethyl-N-beta-hydroxyethylamino) anilide. USE:A substrate for measuring gamma-GTP active value. The compound has high reactivity of gamma-GTP as a substrate and sufficient solubility and can be measured in a measuring wavelength having longer wavelength area than 410nm. PREPARATION:N-Protected-gamma-L-glutamic anhydride is reacted with a p- phenylenediamine derivative expressed by formula II in a solvent such as chloroform, etc., as necessary in the presence of an acid at 20-100 deg.C and a protecting group such as phthalyl group, etc., is removed from the reaction product to provide the compound expressed by formula I.</p> |
