发明名称 Immunogenic synthetic peptide capable of eliciting herpes simplex virus neutralizing antibody
摘要 A synthetic peptide, containing the predicted amino acid residues 64 to 77 of the herpes simplex virus type 1 (HSV1) gB structural glycoprotein open reading frame, a synthetic subunit immunogen that stimulates an immune response against HSV1 and which, when prepared, and chemically-conjugated to a protein carrier molecule, and inoculated into test animals, gives rise to a specific anti-peptide IgG response, such that these anti-peptide antibodies react with a purified HSV-specific structural glycoprotein preparation and are capable of neutralizing the infectivity of HSV1.
申请公布号 US4761470(A) 申请公布日期 1988.08.02
申请号 US19870036651 申请日期 1987.04.10
申请人 MERCK & CO., INC. 发明人 EMINI, EMILIO A.;LARSON, VIVIAN M.;BOGER, JOSHUA S.
分类号 C07K14/035;C07K16/08;(IPC1-7):C07K7/08 主分类号 C07K14/035
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