发明名称 Phospholipid analogs useful as PAF synthesis inhibitors
摘要 There are disclosed phospholipid analogs which are useful as PAF synthesis inhibitors. These compounds inhibit PAF (platelet-activating factor) biosynthesis and are thereby useful in the treatment of various diseases or disorders mediated by the PAF such as, for example, pain, fever, inflammation, cardiovascular disorder, asthma, lung edema, allergic disorders, skin diseases, psoriasis, and adult respiratory distress syndrome.
申请公布号 US4761404(A) 申请公布日期 1988.08.02
申请号 US19850750435 申请日期 1985.07.01
申请人 MERCK & CO., INC. 发明人 BUGIANESI, ROBERT L.;PONPIPOM, MITREE M.;RUPPRECHT, KATHLEEN M.
分类号 C07D521/00;A61K31/10;A61K31/13;A61K31/16;A61K31/17;A61K31/27;A61K31/275;A61K31/33;A61K31/445;A61K31/575;A61K31/655;A61K31/66;A61K31/675;A61K31/685;A61P7/02;A61P9/08;A61P9/10;A61P11/00;A61P25/04;A61P29/00;A61P43/00;C07C45/29;C07C49/255;C07C67/00;C07C313/00;C07C317/18;C07C317/44;C07C325/00;C07C381/00;C07F9/09;C07F9/10;C07F9/32;C07F9/38;C07F9/40;C07F9/572;C07F9/58;C07F9/6533;C07J9/00;(IPC1-7):A61K31/685 主分类号 C07D521/00
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