Nasal compositions containing vitamin B12

摘要

A therapeutic compsn. for nasal admin. comprises vitamin B12 in an isotonic aq. buffer at pH 4-6 contg. sufficient thickening agent so that the viscosity is 2500-6500 cps. The compsn. may also contain 1-10 wt.% humectant and 0.2-2 wt.% surfactant. The vitamin B12 is cyanocobalamin in an amt. of 50-1000 micron and the thickening agent is methyl cellulose. Typically the concn. of the B12 is 0.05-1 wt.%.