发明名称 4H-BENZO(4,5)CYCLOHEPTA(1,2-B)THIOPHENE DERIVATIVES
摘要 (2-Halo-10-oxy-4H -benzo(4,5)cyclohepta(1,2b) thiophen-4-ylidene) acetic acids (I) and their hydrolysable esters and salts are new. (I) is esp. a cpd. of formula (Ia). R1 = H or 1-4C alkyl; R2 = halogen. - 2-Chloro-10-methoxy-4H-benzo (4,5)cyclohepta(1,2-b)thiophen- 4-ylidene) acetic acid (Ib) and the corresp. 4-bromo cpds., and their Et esters are specifically claimed. The cpds. are esp. in cis-iso-meric form.
申请公布号 ZA8609296(B) 申请公布日期 1988.07.27
申请号 ZA19860009296 申请日期 1986.12.09
申请人 SANDOZ LTD. 发明人 ALBERT LEUTWILER
分类号 A61K31/38;A61K31/381;A61P25/04;A61P29/00;C07D333/80 主分类号 A61K31/38
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