摘要 |
1,220,781. Preparation of nitriles. SANDOZ Ltd. 18 March, 1969 [27 March, 1968], No. 14136/69. Heading C2C. Nitriles are prepared by reaction of a carboxylic acid or a salt, acid halide or anhydride thereof, or of a trihalomothyl-substituted aromatic compound, with urea in the presence of aminosulphonic acid. The aminosulphonic acid may be formed in situ by reaction of sulphuric acid with excess urea. |