| 摘要 |
Described is a moisture-vapor-permeable and oxygen-permeable adhesive dressing for use in supplying a topical medicament to human skin in a controlled release manner, which dressing is unaffected by and impermeable to water in the liquid phase, which dressing when in use on human skin consists essentially of: (i) a polymeric backing material lamina (20) having two surfaces, a first substantially planar surface (23) and a second substantially planar surface (25), (ii) adhering to said first planar surface (23) of said backing material a medication reservoir lamina (21) having two surfaces, a first substantially planar surface and a second substantially planar surface (24), consisting essentially of an intimate mixture of: (a) a polyvinyl chloride polymer; (b) a polymeric plasticizer intimately admixed with said polyvinyl chloride and compatible with said polyvinyl chloride; and (c) a topical medicament compatible with said polyvinyl chloride and said plasticizer; said first substantially planar surface of said medication reservoir lamina adhering to said first substantially planar surface of said backing material in a continuous or discontinuous manner, and (iii) adhering to said second substantially planar surface (24) of said medication reservoir lamina, a pressure-sensitive adhesive (22) which is permeable to oxygen and moisture vapor but is unaffected by liquid water. p
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