| 摘要 |
This invention relates to novel 3-thiophene-substituted tryosyl dipeptide amides of the formula: <IMAGE> and the pharmaceutically acceptable addition salts thereof, wherein R1 is -OH, benzyloxy, or -OCH3; wherein R2 and R3 may be the same or different and represent lower alkyl of 1-6 carbon atoms; wherein R4, R5, R6, R7, R8, and R9 may be the same or different and represent hydrogen or lower alkyl of 1-6 carbon atoms; wherein "v" represents an asymmetric carbon atom that may be racemic or that may have the D or L configuration; and wherein "w" represents an asymmetric carbon atom that has the D configuration. These compounds are useful as analgesic agents.
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