| 发明名称 |
Secretion of correctly processed human growth hormone in E. coli and Pseudomonas |
| 摘要 |
The production of mature hGH In E. coli and Pseudomonas strains transformed by a plasmid which encodes pre hGH (comprising the signal polypeptide and the hormone itself) is described. These prokaryotes process the pre-hGH to cleave the signal sequence and, thereby, produce mature hGH.
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| 申请公布号 |
US4755465(A) |
申请公布日期 |
1988.07.05 |
| 申请号 |
US19830488232 |
申请日期 |
1983.04.25 |
| 申请人 |
GENENTECH, INC. |
发明人 |
GRAY, GREGORY L.;HEYNEKER, HERBERT L. |
| 分类号 |
A61K35/74;A61K38/27;C07K14/00;C07K14/575;C07K14/61;C12N1/20;C12N1/21;C12N15/09;C12N15/70;C12N15/78;C12P21/00;C12P21/02;C12R1/19;C12R1/38;(IPC1-7):C12P21/02;C12N15/00 |
主分类号 |
A61K35/74 |
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