发明名称 Novel anticonvulsive tetrahydro-1,2,4-oxadiazine-5-thion derivatives and use
摘要 The present invention relates to novel optically active or racemic tetrahydro-1,2,4-oxadiazine-5-thione derivatives of the formula <IMAGE> (I) methods for their preparation, pharmaceutical compositions comprising the said compounds as active ingredients and a method for the anticonvulsive treatment of mammals, especially human beings. The compounds of the formula I have as good activity as diphenyl hydantoine but their toxicity is much lower.
申请公布号 US4755510(A) 申请公布日期 1988.07.05
申请号 US19850786203 申请日期 1985.10.10
申请人 RICHTER GEDEON VEGYESZETI GYAR R.T.;MTA KOZPONTI KEMIAI KUTATOINTEZETE 发明人 VEZERT NEE SOLYOM, CSILLA;UEROEGDI, LASZLO;KISFALUDY, LAJOS;OTVOES, LASZLO;TEGYEY, ZSUZSANNA;TUEDOES NEE FEUER, HELGA;PALOSI, EVA;RONAI NEE LUKACS, SARA;CHOLNOKY, ESZTER;SZPORNY, LASZLO
分类号 A61K31/535;C07D273/04;(IPC1-7):A61K31/535 主分类号 A61K31/535
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