FOERFARANDE FOER FRAMSTAELLNING AV NYA, TERAPEUTISKT ANVAENDBARA, I VATTEN SVAORLOESLIGA SALTER AV PENICILLANSYRA-1,1-DIOXID.

摘要

Novel 1:2 N,N min -dibenzylethylenediamine, N-benzyl-2-phenylethylamine and dibenzylamine salts of penicillanic acid 1,1-dioxide are prepared which are sparingly soluble in water and therefore valuable as slow release (depot) forms of penicillanic acid 1,1-dioxide, particularly for use in conjunction with slow release (depot) forms of penicillin and cephalosporin antibiotics, in the chemotherapy of bacterial infections in mammals.