发明名称 Theophyllinemethyldithiolan and theophyllinemethyldithianyl derivates, a method for their preparation and pharmaceutical compositions in which they are included.
摘要 <p>New derivatives of theophylline are described, which have the general formula: &lt;CHEM&gt; in which R is selected from the group consisting of 2'-(1'-oxy-1', 3'-dithiolanyl), 2'-(1', 3'-dithiolanyl) and 2'-(1',3'-dithianyl), possibly substituted in position 4'. The derivatives have high antibronchospastic, antitussive and mucolytic activities.</p>
申请公布号 EP0272596(A2) 申请公布日期 1988.06.29
申请号 EP19870118646 申请日期 1987.12.16
申请人 ISTITUTO BIOLOGICO CHEMIOTERAPICO "ABC" S.P.A. 发明人 FRANZONE, JOSE SEBASTIAN;DE VERCELLI,SERGIO
分类号 A61K31/52;A61K31/522;A61P11/08;A61P11/10;A61P11/14;C07D473/08 主分类号 A61K31/52
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