发明名称 IMIDAZO(4,5-B)PYRIDIN-2-ONE DERIVATIVES,THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM
摘要 Imidazo[4,5-b]pyridin-2-one derivatives of the formula (I) <IMAGE> (I) in which n is 2, 3 or 4, x is =CH- or =N-, R1 and R2, which may be the same or different, each represent hydrogen, halogen or (C1-4) alkoxy and either R3 is H or OH and R4 is H, or R3 and R4 together form a direct bond, their enantiomers and their addition salts with pharmaceutically acceptable acids are pharmacologically active, for example as antagonists to histamine and serotonin.
申请公布号 ZA8707532(B) 申请公布日期 1988.06.29
申请号 ZA19870007532 申请日期 1987.10.07
申请人 SYNTHELABO 发明人 PHILIPPE MANOURY;JEAN BINET;ELISABETH DEWITTE
分类号 A61K31/44;A61P37/08;C07D471/04 主分类号 A61K31/44
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