| 发明名称 |
ALLENYLAMINER, FREMGANGSMAADE TIL DERES FREMSTILLING OG FARMACEUTISKE PRAEPARATER DERAF |
| 摘要 |
<p>The present invention relates to compounds which are allenyl amines, more specifically, beta -ethenylidene-(substituted)ethanamines, possessing antihypertensive activity. They are prepared by a novel reaction of a protected N,N-bis-(trimethylsilyl)-4-methoxy-2-butynylamine compound with a metallo-organic compound, with subsequent removal of the silyl protecting groups to provide the desired compound.</p> |
| 申请公布号 |
DK679787(A) |
申请公布日期 |
1988.06.24 |
| 申请号 |
DK19870006797 |
申请日期 |
1987.12.22 |
| 申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
MCCARTY, JAMES R.;BARGAR, THOMAS M.;BARNEY, CHARLOTTE L.;MATTHEWS, DONALD P.;BROERSMA, ROBER J. |
| 分类号 |
C07D233/64;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/415;A61K31/425;A61K31/426;A61K31/44;A61K31/4402;A61K31/4418;A61P9/12;C07D213/38;C07D213/61;C07D213/63;C07D213/70;C07D213/71;C07D213/79;C07D231/10;C07D231/12;C07D233/54;C07D233/70;C07D277/20;C07D277/28;C07D277/32;C07D307/52;C07D307/56;C07D333/20;C07D333/58;(IPC1-7):C07D333/00 |
主分类号 |
C07D233/64 |
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