| 摘要 |
<p>Disclosed is an improved process for encapsulating core materials, particularly viable cells, within a membrane of controlled porosity. A polyanionic polymer, e.g., sodium alginate, is formed into shape-retaining gel masses. The gelled masses are then expanded by hydration, and a membrane is formed by reaction at the surface of the expanded masses with a polyanionic polymer having a molecular weight greater than 3000. The expansion step promotes the formation of continuous, uniform capsule membranes of more consistent permeability resulting in a more reproducible cell encapsulation process.</p> |
