| 摘要 |
PURPOSE:To obtain the titled preparation containing granulocyte colony stimulating factor and at least one saccharide. CONSTITUTION:A stable granulocyte colony stimulating factor (G-CSF)- containing preparation comprising 1pt.wt. G-CSF [e.g. human G-CSF having 19,000+ or -1,000 (by sodium dodecyl sulfate-polyacrylamide gel electrophoresis), at least one isoelectric point of pI=5.5+ or -0.1, pI=5.8+ or -0.1 and pI=6.1+ or -0.1 and an amino acid sequence from N end to 21st having a group shown by the formula] and 1-10,000pts.wt. at least one saccharide (e.g. glycerin, erythritol, heparin, dextrin, arginic acid etc.). The preparation can be used by various administration forms such as oral administration and parenteral administration such as many injections, etc. Adsorption on the wall of container can be prevented and consumption of expensive component can be hindered.
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