NON-RADIOACTIVE NUCLEIC ACID PROBES

摘要

A diazonium compound of formula (I), wherein Z is selected from the group consisting of biotin, an antigen, an antibody, a photoreactive group, a fluorescent group and heavy metal-containing compounds; X is an alkylene group containing up to 18 carbon atoms in the principle chain and a total of up to 24 carbon atoms or a substituted alkylene group containing up to 18 carbon atoms in the principle chain with substituents selected from the group consisting of solubility-enhancing groups and cleavable -S-S- containing moieties; Ar is an unsubstituted or substituted aryl or heteroaryl; and Y is an anion and n is an integer from 1-3.