发明名称 ANTIPSYCHOTIC AMINO-POLYHYDRO-BENZ-(ISO)QUINOLINES AND INTERMEDIATES
摘要 Amino-polyhydro-benz-(iso)quinoline compounds of formula (I), wherein X, Y, Z, R1, R2, R3 are as defined in the specification, e.g., 3aS-trans-5-(N,N-di-n-propylamino)-3a,4,5,6-tetrahydro-1H-benzo de quinolin-2(3H)one, or pharmacologically acceptable salts thereof, are useful as antipsychotic drugs or as intermediates for making such compounds. Pharmaceutical compositions and methods of using these compounds are also provided. Processes for preparing the compounds are provided.
申请公布号 WO8804292(A1) 申请公布日期 1988.06.16
申请号 WO1987US02866 申请日期 1987.11.04
申请人 THE UPJOHN COMPANY 发明人 SZMUSZKOVICZ, JACOB;DARLINGTON, WILLIAM, H.;VON VOIGTLANDER, PHILIP, F.
分类号 C07D221/14;(IPC1-7):C07D221/14;A61K31/435 主分类号 C07D221/14
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