发明名称 |
Use of cartilage-inducing factor B (cif-B) for the manufacture of a medicament for inhibiting tumor growth. |
摘要 |
<p>A polypeptide called cartilage-inducing factor B (CIF-B) or transforming growth factor beta 2 (TGF- beta 2) that is found in bone and has heretofore been identified as having in vitro cartilage-inducing activity, TGF- beta activity, and anti-inflammatory activity has now been found to possess potent oncostatic activity. CIF-B showed oncostatic activity on human and animal tumors, including carcinomas, adenocarcinomas, lymphomas, and melanomas.</p> |
申请公布号 |
EP0271211(A2) |
申请公布日期 |
1988.06.15 |
申请号 |
EP19870309877 |
申请日期 |
1987.11.06 |
申请人 |
COLLAGEN CORPORATION;ONCOGEN |
发明人 |
MCPHERSON, JOHN M.;TWARDZIK, DANIEL R.;TODARO, GEORGE J.;PIEZ, KARL A.;RANCHALIS, JANE E. |
分类号 |
A61K38/22;A61K38/00;A61K38/18;A61P35/00 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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