| 摘要 |
1-Aryloxy-4-[(4-aryl)-1-piperazinyl]-2-butanols of the formula: <CHEM> wherein Ar is selected from <CHEM> or 2, 3 or 4-pyridyl); X and X' are selected from the group of hydrogen, loweralkyl, loweralkoxy, halogen, trifluoromethyl, nitro, acetylamino, phenyl or <CHEM> acetyl, cyano, aminocarbonyl, carboxy, or loweralkyl carboxylic acid ester; Y, Y', Y'' and X'' are selected from the same group as X and X' except phenyl and substituted phenyl are excluded; Z and Z' are selected from hydrogen, loweralkyl or loweralkoxy and the pharmaceutically acceptable salt thereof are useful in inhibiting or combatting allergic response associated with anaphylactic sensitivity in animals and humans. |
