Fluoro coumarins as antilymphoedema agents

摘要

A compound of the formula <IMAGE> wherein hydrogen, fluorine, chlorine or bromine; B is fluorine, or when A is fluorine B may be hydrogen; R is hydrogen, C1-C8 branched or unbranched alkyl, CH2BR, CH2Cl or substituted or unsubstituted phenyl; X is hydrogen, chlorine or bromine; one of R1 and R2 is hydrogen and the other is hydroxy or C1-C7 branched or unbranched alkoxy unsubstituted or substituted by a dialkyl amino group, or R1 and R2, taken together with the carbon atom to which they are linked, form the group <IMAGE> with the proviso that, when R and X are both hydrogen, <IMAGE> is a <IMAGE> group, and B is fluorine and A is hydrogen is useful as antilimphoedema agent.