| 摘要 |
PURPOSE:To obtain a treating and preventive agent for peptic ulcer, containing a cyclohexane derivative as an active ingredient, having low toxicity as well as excellent antiulcer activity and particularly useful also for ethanol or serotonin ulcer. CONSTITUTION:A treating and preventive agent for peptic ulcer obtained by blending a cyclohexane derivative expressed by the formula [X is =CH=CH-, ethynylene, vinylene or ethylene; Y is oxo or OH; R<1>-R<5> are H or alkyl; R<6> is oxo or -OR<8>; R<7> is H or -OR<8> (R<8> is H or organic residue)] as an active ingredient with a carrier, excipient, diluent, etc., and formulating the resultant blend into a pharmaceutical by a conventional method. The dose thereof is 0.1-0.5mg as the compound expressed by the formula per day for an adult administered once - in several divided portions. 4-(1,4-Dihydroxy-2,6,6- trimethylcyclohexyl)but-3-yn-2-ol is exemplified as the compound expressed by the formula.
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