| 摘要 |
A medical construction material consists of a polymer whose repeating units possess a functional group to which is bound a macromer by the reactive terminal gp. at one end of the macromer forming a graft layer; at the other end of the macromer is bound a fat-sol vitamin or an (un)satd. fatty acid. The polymer may be cellulose or regenerated cellulose possessing amino, carboxy or (esp.) hydroxy gps. The fat-sol vitamin may be vitamin A, D, E or K or ubiquinone (pref. vitamin E); the fatty acid may be lauric, myristic, pentadecanoic, palmitic, stearic, ellagic, oleic, linoleic, linolenic, arachidonic or eicosapentaenoic acid (pref. myristic, palmitic, linolenic or linoleic). The macromer may be an epoxide or an alkylene glycol (e.g., a diglycidyl ether or a 1-100 unit (poly)alkylene glycol, such as 1,4-butanediol diglycidyl ether, polyethylene glycol or polypropylene glycol). The macromer may be bound to the polymer by reaction in the presence of alkaline catalyst (e.g., NaOH or KOH) or a Friedel-Crafts catalyst (e.g., boron trifluoride) in a solvent such as dioxane, acetone or butanone. |
