发明名称 CHROMENE COMPOUND
摘要 NEW MATERIAL:The compound of formula (R<1> is H or alkyl; R<2> is H or acyl). EXAMPLE:6-Hydroxy-7- methoxy-2-methyl-2-( 4-methylpent-3-enyl )-2H-1-benzopy- ran. USE:A preventive and remedy for adult diseases active to inhibit the production of lipid peroxide. PREPARATION:The compound of formula can be produced e.g. by extracting Amaroucium multiplicatum belonging to Amaroucium genus, Polychrini family, Ascidiaceae order, Urochordacea class, Prochordata subkingdom with a hydrophilic solvent such as methanol, washing with n-hexane to remove an n-hexane-soluble fraction and purifying the product by silica gel column chromatography.
申请公布号 JPS63130590(A) 申请公布日期 1988.06.02
申请号 JP19860276281 申请日期 1986.11.19
申请人 SANKYO CO LTD 发明人 SATOU KATSUYA;SHINDO TAKAMASA;TERAHARA AKIRA;HASEGAWA KAZUO
分类号 A61K31/35;A61K31/352;A61P3/06;C07D311/72 主分类号 A61K31/35
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