发明名称 ENHANCING GAMMA-CARBOXYLATION OF RECOMBINANT VITAMIN K-DEPENDENT PROTEINS
摘要 <p>A DNA sequence including a first DNA sequence encoding a human vitamin K-dependent protein having fused to its 5' end a second DNA sequence not identical to the propeptide encoding sequence naturally associated with the DNA sequence encoding the protein, the non-naturally occuring propeptide encoding sequence being capable of encoding a propeptide which is capable of enhancing the gamma-carboxylation of the protein when the protein is expressed in a recombinant eukaryotic cell.</p>
申请公布号 WO1988003926(A1) 申请公布日期 1988.06.02
申请号 US1987003015 申请日期 1987.11.17
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