| 摘要 |
<p>Compounds of Formula (I) S-(CH2)n-A (I) in which S is a 17-spartein nucleus n is 0 or 1 and A is 2-furyl, 2-thienyl or 2-(N-alkyl)pyrryl when n=0, or 3-furyl or 3-thienyl when n=1, or pyridyl or a phenyl group of Formula (II) <IMAGE> (II) in which at least one of R1, R2 and R3 is a defined substituent other than hydrogen. Such compounds and corresponding compounds in which A is an unsubstituted phenyl group are useful in pharmaceutical compositions as heart affecting agents. Methods of preparing such compounds and pharmaceutical compositions are also disclosed.</p> |
