发明名称 Treatment of disease conditions relating to hyperactive organelles.
摘要 <p>Disease conditions resulting from the hyperactivity or organelles are treated by administering either percarboxcylic acids or kojic acid esters in an appropriate formulation. The percarboxcylic acids or those of the formula R-[- @-O-OH]n in which R is alkyl, alkenyl, aryl, heteroaryl and substituted derivatives thereof, and n is 1 or 2. The kojic acid esters are those having the formula &lt;CHEM&gt; in which X is H or R&lt;2&gt;- @-, and R&lt;1&gt; and R&lt;2&gt; are either alkyl, alkenyl, or substituted derivatives thereof. These compounds, as well as dicarboxylic acids, also function as carriers for toxic therapeutic agents, to enhance the penetration of such agents into the organelles while inhibiting their toxicity to the host organism.</p>
申请公布号 EP0268907(A2) 申请公布日期 1988.06.01
申请号 EP19870116450 申请日期 1987.11.06
申请人 THORNFELDT, CARL RICHARD 发明人 THORNFELDT, CARL RICHARD
分类号 A61K31/185;A61K31/19;A61K31/20;A61K31/34;A61K31/35;A61K31/351;A61K31/455;A61P29/00;A61P31/04;A61P35/00;A61P43/00;C07D309/38 主分类号 A61K31/185
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