发明名称 |
Cytotoxic conjugates useful in therapy, and process for obtaining them. |
摘要 |
<p>Immunotoxins formed by covalent coupling between, on the one hand, the A chain of ricin as such or correctly modified and, on the other hand, an antibody or antibody fragment, employed in its natural form or correctly modified, having the capacity of selectively recognising an antigen carried by the intended target cells. The coupling is produced by means of a thioether bond.</p> |
申请公布号 |
EP0269188(A2) |
申请公布日期 |
1988.06.01 |
申请号 |
EP19870202356 |
申请日期 |
1985.06.18 |
申请人 |
SANOFI |
发明人 |
JANSEN, FRANZ K.;GROS, PIERRE |
分类号 |
A61K36/00;A61K36/18;A61K36/42;A61K38/00;A61K38/16;A61K38/36;A61K39/395;A61K47/00;A61K47/48;A61P35/00;C07D521/00;C07K1/107;C07K1/113;C07K14/00;C07K14/415;(IPC1-7):C07K15/00 |
主分类号 |
A61K36/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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