发明名称 Cytotoxic conjugates useful in therapy, and process for obtaining them.
摘要 <p>Immunotoxins formed by covalent coupling between, on the one hand, the A chain of ricin as such or correctly modified and, on the other hand, an antibody or antibody fragment, employed in its natural form or correctly modified, having the capacity of selectively recognising an antigen carried by the intended target cells. The coupling is produced by means of a thioether bond.</p>
申请公布号 EP0269188(A2) 申请公布日期 1988.06.01
申请号 EP19870202356 申请日期 1985.06.18
申请人 SANOFI 发明人 JANSEN, FRANZ K.;GROS, PIERRE
分类号 A61K36/00;A61K36/18;A61K36/42;A61K38/00;A61K38/16;A61K38/36;A61K39/395;A61K47/00;A61K47/48;A61P35/00;C07D521/00;C07K1/107;C07K1/113;C07K14/00;C07K14/415;(IPC1-7):C07K15/00 主分类号 A61K36/00
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